Live. Work. Play. Learn Known by natives as Downtown Miami, the Central Business District (CBD) of Miami is bounded by NE 6th Street to the North, Biscayne Bay to the east, the Miami River to the West. About Central Business District real estate & condos: The Central Business District is home to the historic Flagler Street shopping district, Government Center, Metrorail hub, office buildings, libraries and college campuses. Simply put, many things worth doing Downtown are located within the limits of the Central Business District. The residential component is growing. One Miami condominium started it all with the first residential building inside the Central Business District in 2005. Since then, many signature residential options have been added like the Epic Hotel and Condominiums and the Met complex.